| 刘书花,吕功煊,鲜亮.NMR研究水溶液中L-精氨酸与磷酸腺苷的相互作用及其构象变化[J].分子催化,2006,(1):57-61 |
| NMR研究水溶液中L-精氨酸与磷酸腺苷的相互作用及其构象变化 |
| NMR Studies on Conformational Change of L-Arginine Induced by the Interaction with Adenosine phosphate in Aqueous Solution |
| 投稿时间：2005-04-01 修订日期：2005-05-16 |
| DOI： |
| 中文关键词: L-精氨酸,磷酸腺苷,氢键,构象变化,化学位移 |
| 英文关键词:L-Arginine,Adenosine phosphate,hydrogen-bonding,Conformation change,Chemical shift |
| 基金项目: |
| 刘书花 吕功煊 鲜亮 |
| 中国科学院兰州化学物理研究所羰基合成与选择氧化国家重点实验室 甘肃兰州730000 |
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| 中文摘要: |
| 利用核磁共振(NMR)方法,研究了水溶液中L-精氨酸分别与一磷酸腺苷、三磷酸腺苷的相互作用及其构象变化.通过测定L-精氨酸分别与一磷酸腺苷、三磷酸腺苷混合后体系的1H、13C NMR,对混合前后L-精氨酸1H及13C化学位移变化情况进行了分析,发现L-精氨酸与一磷酸腺苷、三磷酸腺苷存在氢键和静电作用,并且这种相互作用会导致L-精氨酸构象产生变化,即由作用之前的伸展型转变为作用后的弯曲型. |
| 英文摘要: |
| In this paper, the conformational change of L-Arginine induced by the interaction with Adenosine phosphate in aqueous solution was studied by using NMR technique. The changes of ^1H, ^13C chemical shifts of L-Arglnine due to the presence of Adenosine phosphate were measured. It found that there is interaction of hydrogenbonding and electrostatic attraction between L-Arginine and Adenosine phosphate. Conformational change of L-Ar- ginine molecular have been leaded from this interaction. |
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